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Calcium carbonate + chitosan (brand name Epakitin®) is a phosphorus binder and calcium supplement. It is used to treat high blood phosphorus levels in cats and dogs with chronic kidney disease and to treat low blood calcium levels in cats, dogs, and other species.
The U.S. Food and Drug Administration (FDA) does not review non-drug health products (e.g., herbals, nutraceuticals, shampoos, and other supplements) for safety or effectiveness before they are sold to the public. Manufacturers of non-drug health products must ensure their products are safe and labeled accurately.
The FDA requires that these non-pharmaceuticals contain a disclaimer that says, “This product is not intended to diagnose, treat, cure or prevent any disease.” Health Canada licenses “veterinary health products” after reviewing safety, efficacy, and manufacturing information provided by the manufacturer. These products are not tested by Health Canada.
> “Your veterinarian is the best source of information > > about the safety of non-drug health products in pets.”Your veterinarian is the best source of information about the safety of non-drug health products in pets. Just because a product is natural does not mean it is safe. All medicines and medicinal plants are potentially toxic if used inappropriately or given at high doses. Supplements can also have side effects, like pharmaceuticals. Few supplements and herbs have been subjected to rigorous scientific trials to determine their efficacy.
Although the information in this handout may be helpful, it also may be incomplete and may not represent the full range of effects the supplement could have on your pet.
This medication should take effect within 1 hour.
If you miss a dose, give it as soon as you remember and then wait the recommended time as prescribed by your veterinarian for the next dose. Do not give the pet two doses at once.
Calcium carbonate + chitosan may cause the following side effects:
The following reactions are rare, but if they occur, contact your veterinarian immediately:
Drug sensitivities can develop over time with repeated exposure. Your pet may have no reaction after the first few doses but may develop a sensitivity later. It is important to watch for signs of an allergic reaction over the entire course of treatment.
Other side effects may occur. If you notice anything unusual, contact your veterinarian immediately. This medication is short-acting, meaning that effects will last less than 24 hours, though effects may last longer in pets with kidney or liver disease.
Calcium carbonate + chitosan should NOT BE USED in pets who:
Calcium carbonate + chitosan should be USED WITH CAUTION in pets who are taking calcitriol.
Certain medications should be USED WITH CAUTION when given with calcium carbonate + chitosan, including:
Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking before starting any new treatment.
© Copyright 2025 LifeLearn Inc. Used and/or modified with permission under license. This content written by LifeLearn Animal Health (LifeLearn Inc.) is licensed to this practice for the personal use of our clients. Any copying, printing or further distribution is prohibited without the express written consent of LifeLearn. This content does not contain all available information for any referenced medications and has not been reviewed by the FDA Center for Veterinary Medicine, or Health Canada Veterinary Drugs Directorate. This content may help answer commonly asked questions, but is not a substitute for medical advice, or a proper consultation and/or clinical examination of your pet by a veterinarian. Please contact your veterinarian if you have any questions or concerns about your pet’s health. Created on Oct 2, 2024.
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2801 Keele St. Unit #101 Downsview, ON M3M 2G6
Phone: 416- 633-2255
Fax: 416-633-2305
E-Mail: downsviewveterinary@bellnet.ca
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