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Itraconazole

What is itraconazole?

Itraconazole (brand names: Itrafungol®, Sporanox®, Onmel®) is a systemic antifungal medication used to treat fungal infections such as ringworm and blastomycosis. Its use in dogs, small mammals, and some exotics to treat fungal infections is “off label” or “extra label”. Use of the human version of this drug is “off label” or “extra label” in cats and dogs. Many drugs are commonly prescribed for off-label use in veterinary medicine. In these instances, follow your veterinarian’s directions and cautions carefully, as they may be significantly different from those on the label.

How is itraconazole given?

This medication should not be compounded, as compounds prepared from bulk chemical are unlikely to be effective.

What if I miss giving my pet the medication?

If you miss a dose, give it as soon as you remember, and then continue with the regular dosing schedule. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not give the pet two doses at once.

Are there any potential side effects?

Itraconazole may cause the following side effects:

Other side effects may occur. If you notice anything unusual, contact your veterinarian immediately. This medication can take a few weeks before full effects are observed, but gradual improvements are usually noticeable after a few days.

This moderate-acting medication should stop working in a few days, although effects can be longer in pets with liver or kidney disease.

Are there any risk factors for this medication?

Itraconazole should NOT BE USED by pets that are allergic to it or similar antifungals.

It should be USED WITH EXTREME CAUTION in pets:

It should be USED WITH CAUTION in pets:

Are there any drug interactions I should be aware of?

The following medications should be used with caution when given with itraconazole:

Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking before starting any new treatment.

Is there any monitoring that needs to be done with this medication?

How do I store itraconazole?

What should I do in case of emergency?

If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility.

© Copyright 2025 LifeLearn Inc. Used and/or modified with permission under license. This content written by LifeLearn Animal Health (LifeLearn Inc.) is licensed to this practice for the personal use of our clients. Any copying, printing or further distribution is prohibited without the express written consent of LifeLearn. This content does not contain all available information for any referenced medications and has not been reviewed by the FDA Center for Veterinary Medicine, or Health Canada Veterinary Drugs Directorate. This content may help answer commonly asked questions, but is not a substitute for medical advice, or a proper consultation and/or clinical examination of your pet by a veterinarian. Please contact your veterinarian if you have any questions or concerns about your pet’s health. Last updated on Jul 9, 2024.

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